Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10459138 | 0.98 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3OPRD1MEN1 | |
| SCHEMBL21381830 | 0.93 | OPRD1 (0.57) | SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL21385215 | 0.93 | OPRD1 (0.57) | SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL30149811 | 0.93 | OPRD1 (0.57) | SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL21384835 | 0.93 | OPRD1 (0.57) | SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL21382071 | 0.91 | ACHE (0.43) | SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL29734367 | 0.91 | ACHE (0.43) | SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL21382142 | 0.91 | ACHE (0.43) | SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL21382069 | 0.91 | ACHE (0.43) | SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL22542178 | 0.86 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3OPRD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4306063-A | 4-Substituted 3,5-morpholinediones | MCNEIL LABORATORIES, INC. (US) | 1981-12-15 | — | — | US | disclosed |
| US-4256891-A | (2-Amino-2-oxoethoxy)acetic acid compounds | MCNEIL LABORATORIES, INC. (US) | 1981-03-17 | — | — | US | disclosed |
| US-4203991-A | (Piperidino oxoethoxy)acetic acid compounds, compositions and methods | MCNEILAB, INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4197315-A | (2-Amino-2-oxoethoxy)acetic acid compounds, compositions and methods | MCNEIL LABORATORIES, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4123538-A | (2-Amino-2-oxoethoxy)acetic acid compounds, compositions and methods | MCNEIL LABORATORIES, INCORPORATED (US) | 1978-10-31 | — | — | US | disclosed |