Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461500 | 1.00 | MAOB (0.64) | MAOBKMT2APRSS1MEN1TSHR | |
| SCHEMBL10460872 | 0.98 | KMT2A (0.64) | MAOBKMT2APRSS1MEN1TSHR | |
| SCHEMBL29842346 | 0.94 | KMT2A (0.66) | MAOBKMT2APRSS1MEN1TSHR | |
| SCHEMBL470710 | 0.94 | KMT2A (0.66) | MAOBKMT2APRSS1MEN1TSHR | |
| SCHEMBL1544858 | 0.91 | KMT2A (0.62) | MAOBKMT2APRSS1MEN1TSHR | |
| SCHEMBL6856717 | 0.89 | KMT2A (0.76) | MAOBKMT2APRSS1MEN1TSHR | |
| SCHEMBL1545288 | 0.87 | KMT2A (0.64) | MAOBKMT2APRSS1MEN1TSHR | |
| SCHEMBL22502336 | 0.87 | THRA (0.64) | MAOBKMT2APRSS1MEN1TSHR | |
| SCHEMBL4375986 | 0.85 | MAPT (0.59) | MAOBKMT2APRSS1TSHRTHRA | |
| SCHEMBL1545237 | 0.85 | TSHR (0.69) | PRSS1TSHRMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |