Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3994942 | 0.92 | KMT2A (0.75) | KMT2AMEN1MAOBPRSS1TSHR | |
| SCHEMBL10260429 | 0.92 | KMT2A (0.66) | KMT2AMEN1MAOBPRSS1TSHR | |
| SCHEMBL4001162 | 0.92 | KMT2A (0.66) | KMT2AMEN1MAOBPRSS1TSHR | |
| SCHEMBL470710 | 0.92 | KMT2A (0.66) | KMT2AMEN1MAOBPRSS1TSHR | |
| SCHEMBL29842346 | 0.92 | KMT2A (0.66) | KMT2AMEN1MAOBPRSS1TSHR | |
| SCHEMBL6973871 | 0.91 | KMT2A (0.64) | KMT2AMEN1MAOBPRSS1TSHR | |
| SCHEMBL10460872 | 0.91 | KMT2A (0.64) | KMT2AMEN1MAOBPRSS1TSHR | |
| SCHEMBL22502336 | 0.91 | THRA (0.64) | KMT2AMEN1MAOBPRSS1TSHR | |
| SCHEMBL20143893 | 0.91 | KMT2A (0.64) | KMT2AMEN1MAOBPRSS1TSHR | |
| SCHEMBL1545288 | 0.91 | KMT2A (0.64) | KMT2AMEN1MAOBPRSS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012123963-A2 | A PROCESS FOR PREPARATION OF ILOPERIDONE AND AMORPHOUS CO- PRECIPITATE OF ILOPERIDONE WITH PHARMACEUTICALLY ACCEPTABLE EXCIPIENT | MEGAFINE PHARMA (P) LTD. (IN) | 2012-09-20 | — | — | WO | disclosed |
| WO-2011154860-A1 | AN IMPROVED PROCESS FOR PREPARING ILOPERIDONE | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011055188-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF ILOPERIDONE | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |