Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459179 | 0.87 | S1PR1 (0.46) | PPARACYP4F2CYP4A11LMNA | |
| SCHEMBL5892307 | 0.86 | PPARA (0.49) | PPARACYP4F2CYP4A11TSHRTDP1 | |
| SCHEMBL8621200 | 0.86 | PPARA (0.49) | PPARACYP4F2CYP4A11TSHRTDP1 | |
| SCHEMBL10459075 | 0.84 | L3MBTL1 (0.59) | PPARACYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL8617055 | 0.82 | CYP4F2 (0.52) | PPARACYP4F2CYP4A11CYP3A4LMNA | |
| SCHEMBL8624692 | 0.81 | PPARA (0.45) | PPARACYP4F2CYP4A11LMNA | |
| SCHEMBL10457436 | 0.81 | PPARA (0.49) | PPARACYP4F2CYP4A11KMT2AMEN1 | |
| SCHEMBL10458719 | 0.81 | MAPT (0.60) | PPARACYP4F2CYP4A11LMNAKMT2A | |
| SCHEMBL9786355 | 0.81 | CYP4F2 (0.50) | PPARACYP4F2CYP4A11TSHRTDP1 | |
| SCHEMBL9786303 | 0.81 | CYP4F2 (0.54) | PPARACYP4F2CYP4A11TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942242-A | ANTICHOLESTEROL AGENTS | KOJIMA TADAO (JP) | 1990-07-17 | — | — | US | disclosed |
| US-4798838-A | ANTICOAGULANTS, ANTICHOLESTEROL AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-01-17 | — | — | US | disclosed |
| US-4795753-A | Certain pyridyl or imidazol-1-yl-alkyleneoxy-(or amino)phenoxy-alkanoates having lipid lowering activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| US-4794113-A | ANTICHOLESTEROL, ANTILIPEMIC, ANTICOAGULANT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-12-27 | — | — | US | disclosed |
| EP-0130077-A2 | Phenoxy derivatives, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |