Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621200 | 0.89 | PPARA (0.49) | PPARACYP4F2CYP4A11 | |
| SCHEMBL8617055 | 0.88 | CYP4F2 (0.52) | PPARACYP4F2CYP4A11S1PR1S1PR4 | |
| SCHEMBL10459179 | 0.87 | S1PR1 (0.46) | PPARACYP4F2CYP4A11S1PR1S1PR4 | |
| SCHEMBL9786303 | 0.84 | CYP4F2 (0.54) | PPARACYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL8057272 | 0.84 | PPARA (0.63) | PPARAS1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL10457436 | 0.82 | PPARA (0.49) | PPARACYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL5892307 | 0.81 | PPARA (0.49) | PPARACYP4F2CYP4A11 | |
| SCHEMBL10459356 | 0.81 | PPARA (0.49) | PPARACYP4F2CYP4A11LMNA | |
| SCHEMBL22922179 | 0.80 | CYP4F2 (0.57) | PPARACYP4F2CYP4A11 | |
| SCHEMBL10459075 | 0.80 | L3MBTL1 (0.59) | PPARACYP4F2CYP4A11LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5734077-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, TREATMENT OF DIABETES AND ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 1998-03-31 | — | — | US | disclosed |