Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457425 | 0.87 | PPARA (0.74) | PPARANPC1KDM4EMEN1KMT2A | |
| SCHEMBL10457428 | 0.84 | PPARA (0.52) | PPARAMAPT | |
| SCHEMBL3656838 | 0.83 | NPC1 (0.56) | NPC1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL10683854 | 0.81 | PPARA (0.62) | PPARANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27090651 | 0.81 | L3MBTL1 (0.49) | PPARAMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL10685340 | 0.80 | SMN1; SMN2 (0.51) | PPARANPC1KDM4EMEN1KMT2A | |
| SCHEMBL10459131 | 0.80 | PPARA (0.51) | PPARAMAPT | |
| SCHEMBL21991363 | 0.80 | MAOB (0.55) | PPARANPC1KMT2ARAB9AMAOB | |
| SCHEMBL17028385 | 0.80 | ELANE (0.51) | KDM4EMEN1KMT2ALMNAMAOB | |
| SCHEMBL23577314 | 0.79 | LMNA (0.55) | PPARAMEN1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942242-A | ANTICHOLESTEROL AGENTS | KOJIMA TADAO (JP) | 1990-07-17 | — | — | US | disclosed |
| US-4798838-A | ANTICOAGULANTS, ANTICHOLESTEROL AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-01-17 | — | — | US | disclosed |
| US-4795753-A | Certain pyridyl or imidazol-1-yl-alkyleneoxy-(or amino)phenoxy-alkanoates having lipid lowering activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| US-4794113-A | ANTICHOLESTEROL, ANTILIPEMIC, ANTICOAGULANT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-12-27 | — | — | US | disclosed |