Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | BRD4 | O60885 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | EDNRA | P25101 | 1/20 | 0.63 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.63 |
| ▸ | TOP2A | P11388 | 5/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312379 | 0.92 | KDM4E (0.76) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| Water SCHEMBL10765060 | 0.91 | KDM4E (0.75) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL10743594 | 0.91 | KDM4E (0.77) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10769533 | 0.90 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10765880 | 0.89 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL10765706 | 0.88 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL10768278 | 0.88 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL10764169 | 0.88 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10401471 | 0.88 | KDM4E (0.63) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL11022192 | 0.88 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237955-A2 | Quinolonecarboxylic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | claimed |
| US-4894458-A | BACTERICIDES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0237955-A2 | Quinolonecarboxylic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |