Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.71 |
| ▸ | HPGD | P15428 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | EDNRA | P25101 | 1/20 | 0.61 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.61 |
| ▸ | TOP2A | P11388 | 5/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312379 | 0.96 | KDM4E (0.76) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| Hydrochloric Acid SCHEMBL10743594 | 0.95 | KDM4E (0.77) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| Water SCHEMBL10765060 | 0.95 | KDM4E (0.75) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL11185030 | 0.91 | KDM4E (0.71) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL10459451 | 0.88 | KDM4E (0.65) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL10769533 | 0.88 | KDM4E (0.65) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL10765880 | 0.87 | KDM4E (0.64) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| Hydrochloric Acid SCHEMBL11187466 | 0.87 | KDM4E (0.68) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL6305606 | 0.87 | KDM4E (0.80) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| Hydrochloric Acid SCHEMBL10764169 | 0.86 | KDM4E (0.65) | KDM4EHSD17B10HPGDALDH1A1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60006684-A | — | — | None | — | — | JP | disclosed |
| JP-S606684-A | 7-HOMOPIPERAZINE-SUBSTITUTED-6,8-DIFLUORO-4-OXO-1,4- HYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1985-01-14 | — | — | JP | disclosed |