Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
| ▸ | TOP1 | P11387 | 4/20 | 0.59 |
| ▸ | TOP2A | P11388 | 12/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369381 | 0.94 | KDM4E (0.58) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL8699900 | 0.92 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL8566204 | 0.91 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4366154 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4372305 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4372308 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4366156 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL4366152 | 0.90 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL10765055 | 0.90 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL10401542 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4894458-A | BACTERICIDES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-01-16 | — | — | US | claimed |
| CN-87101984-A | Carbostyril carboxylic acid derivatives and preparation method thereof | — | 1987-10-07 | — | — | CN | claimed |
| EP-0237955-A2 | Quinolonecarboxylic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | claimed |
| US-4894458-A | BACTERICIDES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0237955-A2 | Quinolonecarboxylic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |