Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | TOP1 | P11387 | 4/20 | 0.61 |
| ▸ | TOP2A | P11388 | 12/20 | 0.56 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.55 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8566204 | 0.99 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL10459583 | 0.92 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL10765055 | 0.91 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9046371 | 0.91 | KDM4E (0.71) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL10401542 | 0.91 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL10823302 | 0.89 | KDM4E (0.75) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9070334 | 0.88 | KDM4E (0.69) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9145601 | 0.87 | KCNH2 (0.69) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL10618833 | 0.87 | KDM4E (0.68) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL10443590 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753658-A | FOR TREATMENT OF BACTERIAL INFECTIONS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0610896-A1 | Quinolonecarboxylic acid derivatives as antibacterials | Senju Pharmaceutical Co., Ltd. (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0235589-B1 | USE OF QUINOLONE AND NAPHTHYRIDINE ANTIBIOTICS FOR THE MANUFACTURE OF OPHTHALMIC MEDICAMENTS | WARNER-LAMBERT COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |
| US-4851415-A | TOPICAL ADMINISTRATION | WARNER-LAMBERT COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| US-4777175-A | (NAPHTHYRIDINE, QUINOLINE) CARBOXYLIC ACID | WARNER-LAMBERT COMPANY (US) | 1988-10-11 | — | — | US | disclosed |
| US-4771054-A | QUINOLINE CARBOXYLIC ACID | WARNER-LAMBERT COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0106489-B1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |
| EP-0235589-A2 | Use of quinolone and naphthyridine antibiotics for the manufacture of ophthalmic medicaments | WARNER-LAMBERT COMPANY (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4692454-A | Opthalmic use of quinolone antibiotics | WARNER-LAMBERT COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| US-4665079-A | QUINOLINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| US-4638067-A | NAPHTHYRIDINE AND QUINOLINE CARBOXYLIC ACIDS | WARNER-LAMBERT CO. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0153163-A2 | 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| EP-0106489-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |