SCHEMBL10459771

SCHEMBL10459771

COc1ccc(-c2ccc(C(=O)NC(C)CCCc3cccnc3)cc2-c2ccc(OC)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10459769 1.00 PTAFR (0.81) PTAFR
SCHEMBL10459682 0.91 PTAFR (0.82) PTAFR
SCHEMBL10459683 0.91 PTAFR (0.82) PTAFR
SCHEMBL10459236 0.89 PTAFR (0.84) PTAFR
SCHEMBL10459235 0.89 PTAFR (0.84) PTAFR
SCHEMBL10459516 0.82 PTAFR (0.83) PTAFR
SCHEMBL10458010 0.82 PTAFR (0.83) PTAFR
SCHEMBL10459177 0.82 PTAFR (0.83) PTAFR
SCHEMBL10458012 0.82 PTAFR (0.83) PTAFR
SCHEMBL10459706 0.81 PTAFR (1.00) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4916145-A PLATELET ACTIVATING FACTOR ANTAGONISTS HOFFMANN-LA ROCHE INC. (US) 1990-04-10 US disclosed