Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460005 | 0.95 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10972119 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10382723 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10458248 | 0.85 | MAPT (0.52) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10459499 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10755688 | 0.83 | MAPT (0.50) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL54807 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL29373703 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL8535445 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL11088562 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978383-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-12-18 | — | — | US | claimed |
| US-4978383-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-12-18 | — | — | US | disclosed |