Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.63 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412302 | 0.88 | ALDH1A1 (0.79) | ALDH1A1CA1CA2TDP1MAPT | |
| SCHEMBL11340654 | 0.87 | ALDH1A1 (0.69) | ALDH1A1CA1CA2TDP1MAPT | |
| Hydrochloric Acid SCHEMBL3517769 | 0.86 | ALDH1A1 (0.77) | ALDH1A1CA1CA2TDP1MAPT | |
| SCHEMBL10460235 | 0.84 | MEN1 (0.73) | ALDH1A1MAPTTBXA2RPRMT1AKR1C3 | |
| SCHEMBL10463511 | 0.84 | TAAR1 (0.72) | ALDH1A1CA1CA2TDP1MAPT | |
| SCHEMBL11108949 | 0.84 | AKR1C3 (0.72) | ALDH1A1CA1CA2TDP1MAPT | |
| SCHEMBL11109404 | 0.84 | ALDH1A1 (0.91) | ALDH1A1CA1CA2TDP1MAPT | |
| SCHEMBL10461554 | 0.84 | TBXA2R (0.76) | ALDH1A1CA1CA2TDP1MAPT | |
| SCHEMBL14156120 | 0.83 | ALDH1A1 (0.84) | ALDH1A1CA1CA2TDP1MAPT | |
| SCHEMBL6804085 | 0.83 | PRMT1 (0.88) | ALDH1A1CA1CA2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |