Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460235 | 0.84 | MEN1 (0.73) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL19553973 | 0.84 | TAAR1 (0.72) | TAAR1ALDH1A1CYP1A2POLBCYP2D6 | |
| SCHEMBL3913390 | 0.84 | TAAR1 (0.72) | TAAR1ALDH1A1CYP1A2POLBCYP2D6 | |
| SCHEMBL29260042 | 0.84 | ALDH1A1 (0.84) | TAAR1ALDH1A1CYP1A2POLBCYP2D6 | |
| SCHEMBL10460741 | 0.84 | ALDH1A1 (0.69) | TAAR1ALDH1A1POLBTDP1MEN1 | |
| SCHEMBL13073499 | 0.84 | TAAR1 (1.00) | TAAR1ALDH1A1CYP1A2POLBCYP2D6 | |
| SCHEMBL11106576 | 0.84 | TBXA2R (0.75) | TAAR1ALDH1A1CYP1A2POLBCYP2D6 | |
| SCHEMBL3279019 | 0.83 | ALDH1A1 (0.70) | TAAR1ALDH1A1CYP1A2POLBCYP2D6 | |
| SCHEMBL10460390 | 0.83 | TAAR1 (0.58) | TAAR1ALDH1A1CYP1A2POLBCYP2D6 | |
| SCHEMBL10462381 | 0.82 | CYP1A2 (0.72) | TAAR1ALDH1A1CYP1A2POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |