Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462205 | 0.87 | GABRA1 (0.53) | GABRA1GABRG2GABRB3GABRA3LMNA | |
| SCHEMBL10463844 | 0.86 | ALDH1A1 (0.59) | LMNAALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL9333910 | 0.85 | COMT (0.44) | GABRA1GABRG2GABRB3GABRA3LMNA | |
| SCHEMBL10463753 | 0.84 | COMT (0.43) | GABRA1GABRG2GABRB3GABRA3LMNA | |
| SCHEMBL10463752 | 0.81 | COMT (0.42) | GABRA1GABRG2GABRB3GABRA3LMNA | |
| SCHEMBL25533294 | 0.77 | KDM4E (0.53) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10469576 | 0.75 | ALDH1A1 (0.59) | LMNAALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL9065796 | 0.74 | MEN1 (0.50) | GABRA1GABRG2GABRB3GABRA3LMNA | |
| SCHEMBL26031844 | 0.73 | CYP2C19 (0.61) | GABRA1GABRG2GABRB3GABRA3LMNA | |
| SCHEMBL10462419 | 0.73 | ALDH1A1 (0.57) | LMNAALDH1A1GABRA2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |
| EP-0040082-B1 | NOVEL SUBSTITUTED OXONICOTINATES, THEIR USE AS PLANT GROWTH REGULATORS AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
| EP-0040082-A1 | Novel substituted oxonicotinates, their use as plant growth regulators and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1981-11-18 | — | — | EP | disclosed |