Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462485 | 0.91 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL10461455 | 0.89 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL10461128 | 0.89 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL10462990 | 0.89 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL10462380 | 0.88 | METAP2 (0.46) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL9620664 | 0.74 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL2438644 | 0.74 | MAPK1 (0.41) | SMN1; SMN2RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL1897563 | 0.74 | BCHE (0.46) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL31140242 | 0.74 | CYP2D6 (0.61) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL482024 | 0.74 | RAB9A (0.39) | SMN1; SMN2RAB9ANPC1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4913837-A | Heterocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-03 | — | — | US | disclosed |