Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462394 | 0.96 | MCHR1 (0.57) | PPARGMCHR1CYP3A4RXRALMNA | |
| SCHEMBL10461130 | 0.94 | PPARG (0.51) | PPARGMCHR1CYP3A4RXRALMNA | |
| SCHEMBL10462372 | 0.91 | PPARG (0.49) | PPARGMCHR1CYP3A4RXRALMNA | |
| SCHEMBL10463348 | 0.91 | MCHR1 (0.51) | PPARGMCHR1CYP3A4RXRALMNA | |
| SCHEMBL10460099 | 0.90 | MCHR1 (0.57) | PPARGMCHR1CYP3A4RXRAL3MBTL1 | |
| SCHEMBL10462806 | 0.90 | PPARG (0.48) | PPARGMCHR1CYP3A4RXRALMNA | |
| SCHEMBL10461875 | 0.90 | PPARG (0.48) | PPARGMCHR1CYP3A4RXRALMNA | |
| SCHEMBL10463121 | 0.90 | PPARG (0.48) | PPARGMCHR1CYP3A4RXRALMNA | |
| SCHEMBL10461725 | 0.90 | PPARG (0.48) | PPARGMCHR1CYP3A4RXRALMNA | |
| SCHEMBL10460999 | 0.89 | LMNA (0.50) | PPARGMCHR1CYP3A4RXRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4913837-A | Heterocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-03 | — | — | US | disclosed |