Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901104 | 0.81 | — | — | |
| SCHEMBL28147542 | 0.73 | SOS1 (0.41) | SOS1SOS2KDM4EKMT2A | |
| SCHEMBL27350514 | 0.67 | SOS1 (0.47) | SOS1SOS2 | |
| SCHEMBL27901103 | 0.67 | CHRM5 (0.31) | CHRM5CHRM3KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL4591290 | 0.66 | CHRM5 (0.30) | CHRM5CHRM3KDM4EKMT2A | |
| Methylpiperazine SCHEMBL28887896 | 0.64 | CA2 (0.41) | CHRM5CHRM3KDM4EKMT2A | |
| SCHEMBL13735001 | 0.63 | CHRM5 (0.31) | CHRM5CHRM3 | |
| SCHEMBL16825004 | 0.63 | SOS1 (0.42) | SOS1SOS2 | |
| SCHEMBL1120435 | 0.61 | — | — | |
| SCHEMBL2804034 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940793-A | Pharmacologically active piperazino derivatives | RAVIZZA S.P.A. (IT) | 1990-07-10 | — | — | US | disclosed |
| EP-0171636-A1 | Pharmacologically active piperazino derivatives and the process for their preparation | RAVIZZA S.p.A. (IT) | 1986-02-19 | — | — | EP | disclosed |