SCHEMBL1046309

SCHEMBL1046309

CC1(C)C[C@H](O)[C@]2(CO)[C@H](O)C[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@]43C)[C@@H]2C1

nearest known ligand 0.83

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 9/20 0.83
▸ ALOX5 P09917 2/20 0.70
▸ F3 P13726 4/20 0.65
▸ CYP3A4 P08684 2/20 0.65
▸ USP2 O75604 1/20 0.65
▸ LMNA P02545 1/20 0.65
▸ USP7 Q93009 1/20 0.65
▸ SLCO1B3 Q9NPD5 1/20 0.65
▸ SLCO1B1 Q9Y6L6 1/20 0.65
▸ TOP2A P11388 1/20 0.61
▸ AKR1B10 O60218 1/20 0.56
▸ AKR1B1 P15121 1/20 0.56
▸ CES2 O00748 1/20 0.56
▸ CES1 P23141 1/20 0.56
▸ MAPK1 P28482 1/20 0.53
▸ OXTR P30559 1/20 0.53
▸ AVPR1A P37288 1/20 0.53
▸ CD81 P60033 1/20 0.53
▸ SIRT5 Q9NXA8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30893653 1.00 PTPN1 (0.83) PTPN1ALOX5F3CYP3A4USP2
SCHEMBL19284333 0.91 PTPN1 (1.00) PTPN1ALOX5F3CYP3A4USP2
SCHEMBL29934333 0.91 PTPN1 (1.00) PTPN1ALOX5F3CYP3A4USP2
SCHEMBL30222071 0.90 PTPN1 (0.68) PTPN1ALOX5F3CYP3A4USP2
SCHEMBL1050527 0.90 PTPN1 (0.68) PTPN1ALOX5F3CYP3A4USP2
SCHEMBL15132632 0.90 PTPN1 (0.68) PTPN1ALOX5F3CYP3A4USP2
SCHEMBL4324523 0.90 PTPN1 (0.68) PTPN1ALOX5F3CYP3A4USP2
SCHEMBL15883003 0.88 PTPN1 (0.66) PTPN1ALOX5F3CYP3A4USP2
SCHEMBL13559844 0.88 PTPN1 (0.66) PTPN1ALOX5F3CYP3A4USP2
Soyasapogenol B SCHEMBL398310 0.87 ALOX5 (0.78) PTPN1ALOX5F3CYP3A4USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220291237-A1 Gene Expression Inflammatory Age and Its Uses Edifice Health, Inc. (US) 2022-09-15 — — US disclosed
US-20180132516-A1 POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE SENSORYGEN INC (US) 2018-05-17 — — US disclosed
US-20110020226-A1 PARTICLE STRUCTURES COMPRISING STEROLS AND SAPONINS NORDIC VACCINE TECHNOLOGY A/S 2011-01-27 — — US disclosed
US-7713942-B2 Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides NORDIC VACCINE TECHNOLOGY A/S (DK) 2010-05-11 — — US disclosed
EP-2011517-A1 Polynucleotide binding complexes comprising sterols and saponin Nordic Vaccine Technology A/S (DK) 2009-01-07 — — EP disclosed
EP-1377320-B1 POLYNUCLEOTIDE BINDING COMPLEXES COMPRISING STEROLS AND SAPONINS NORDIC VACCINE TECHNOLOGY AS (DK) 2008-10-01 — — EP disclosed
EP-1409009-A1 THERAPEUTICAL VACCINATION Nordic Vaccine Technology A/S (DK) 2004-04-21 — — EP disclosed
EP-1377320-A2 POLYNUCLEOTIDE BINDING COMPLEXES COMPRISING STEROLS AND SAPONINS Nordic Vaccine Technology A/S (DK) 2004-01-07 — — EP disclosed
WO-2002102407-A1 THERAPEUTICAL VACCINATION NORDIC VACCINE TECHNOLOGY A/S (DK) 2002-12-27 — — WO disclosed
WO-2002080981-A2 POLYNUCLEOTIDE BINDING COMPLEXES COMPRISING STEROLS AND SAPONINS NORDIC VACCINE TECHNOLOGY A/S (DK) 2002-10-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020226-A1 PARTICLE STRUCTURES COMPRISING STEROLS AND SAPONINS LSS, SNRPE, HLA-C PTPN1 2398/4885ALOX5 651/4885F3 3104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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