SCHEMBL4324523

SCHEMBL4324523

CC1(C)C[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]4(C)[C@]3(C)C[C@H](O)[C@@]2(CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 12/20 0.68
▸ ALOX5 P09917 2/20 0.65
▸ F3 P13726 3/20 0.60
▸ USP2 O75604 1/20 0.60
▸ LMNA P02545 1/20 0.60
▸ CYP3A4 P08684 1/20 0.60
▸ USP7 Q93009 1/20 0.60
▸ SLCO1B3 Q9NPD5 1/20 0.60
▸ SLCO1B1 Q9Y6L6 1/20 0.60
▸ TOP2A P11388 1/20 0.56
▸ CES2 O00748 1/20 0.54
▸ CES1 P23141 1/20 0.54
▸ AKR1B10 O60218 1/20 0.52
▸ AKR1B1 P15121 1/20 0.52
▸ EGFR P00533 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1050527 1.00 PTPN1 (0.68) PTPN1ALOX5F3USP2LMNA
SCHEMBL15132632 1.00 PTPN1 (0.68) PTPN1ALOX5F3USP2LMNA
SCHEMBL30222071 1.00 PTPN1 (0.68) PTPN1ALOX5F3USP2LMNA
SCHEMBL15883003 0.92 PTPN1 (0.66) PTPN1ALOX5F3USP2LMNA
SCHEMBL13559844 0.92 PTPN1 (0.66) PTPN1ALOX5F3USP2LMNA
Barringtogenol C SCHEMBL1049164 0.91 PTPN1 (0.81) PTPN1ALOX5F3USP2CYP3A4
Barringtogenol C SCHEMBL15132635 0.91 PTPN1 (0.81) PTPN1ALOX5F3USP2CYP3A4
Barringtogenol C SCHEMBL14871943 0.91 PTPN1 (0.81) PTPN1ALOX5F3USP2CYP3A4
SCHEMBL1046309 0.90 PTPN1 (0.83) PTPN1ALOX5F3USP2LMNA
SCHEMBL30893653 0.90 PTPN1 (0.83) PTPN1ALOX5F3USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083753-A1 Compositions for the Treatment of Metabolic Syndrome and Other Metabolic Disorders, and Methods of Manufacture FLORIDA RES GROUP LLC (US) 2026-03-26 — — US disclosed
US-20240114943-A1 TASTE-IMPROVING COMPOSITIONS AND USES THEREOF AMAI PROTEINS LTD. (IL) 2024-04-11 — — US disclosed
EP-4271701-A1 TASTE-IMPROVING COMPOSITIONS AND USES THEREOF Amai Proteins Ltd. (IL) 2023-11-08 — — EP disclosed
US-11432573-B2 Food and beverage sweeteners CAVALERI HEALTH, INC. (CA) 2022-09-06 — — US disclosed
WO-2022144892-A1 TASTE-IMPROVING COMPOSITIONS AND USES THEREOF AMAI PROTEINS LTD. (IL) 2022-07-07 — — WO disclosed
US-20200229475-A1 FOOD AND BEVERAGE SWEETENERS CAVALERI FRANCO (CA) 2020-07-23 — — US disclosed
US-20200154748-A1 FOOD AND BEVERAGE SWEETENERS CAVALERI HEALTH, INC. (CA) 2020-05-21 — — US disclosed
WO-2019018940-A1 FOOD AND BEVERAGE SWEETENERS CAVALERI FRANCO (CA) 2019-01-31 — — WO disclosed
US-20160271199-A1 Taste Modifiers and Therapeutic Methods Thereof Weight Sciences, LLC (US) 2016-09-22 — — US disclosed
US-20090285919-A1 Rice Bran Extracts for Inflammation and Methods of Use Thereof HALPERN, BARUCH 2009-11-19 — — US disclosed
US-20090155388-A1 WEIGHT PHYTO-NUTRACEUTICAL SYNERGISTIC COMPOSITION OLALDE JOSE ANGEL 2009-06-18 — — US disclosed
US-20080160116-A1 Compositions and Methods Comprising Zingiber Species HERBALSCIENCE SINGAPORE PTE. LTD (SG) 2008-07-03 — — US disclosed
WO-2008070783-A2 COMPOSITIONS AND METHODS COMPRISING ZINGIBER SPECIES HERBALSCIENCE SINGAPORE PTE. LTD. (US) 2008-06-12 — — WO disclosed
US-20020187204-A1 Diet composition and method of weight management ALVIAR BARBARA (US) 2002-12-12 — — US disclosed
US-6413545-B1 ADMINISTERING MIXTURE CONTAINING PLANT EXTRACTS; APPETITE SUPPRESSANT ACCESS BUSINESS GROUP INTERNATIONAL LLC 2002-07-02 — — US disclosed
WO-2000012080-A1 DIET COMPOSITION AND METHOD OF WEIGHT MANAGEMENT AMWAY CORPORATION (US) 2000-03-09 — — WO disclosed
EP-0406516-A1 A process for extracting the concentrated gymnemate from gymnema sylvestre and an equipment for using in the process DONG KOOK PHARMACEUTICAL CO., LTD. (KR) 1991-01-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080160116-A1 Compositions and Methods Comprising Zingiber Species AGL, SQLE, RBPJ PTPN1 3368/4885ALOX5 28/4885F3 587/4885
US-20260083753-A1 Compositions for the Treatment of Metabolic Syndrome and Other Metabolic Disorders, and Methods of Manufacture SLC2A4, NPC1L1, SLC2A3 PTPN1 3677/4885ALOX5 217/4885F3 1658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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