Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461125 | 0.92 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNATP53 | |
| SCHEMBL10461761 | 0.91 | TBXA2R (0.56) | ALDH1A1KMT2AMEN1LMNAAKR1C3 | |
| SCHEMBL10463160 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1LMNARECQL | |
| SCHEMBL9718385 | 0.91 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1LMNATP53 | |
| SCHEMBL10463248 | 0.90 | ALDH1A1 (0.64) | ALDH1A1KMT2ALMNAAKR1C3MAPT | |
| SCHEMBL9660574 | 0.86 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1LMNATP53 | |
| SCHEMBL10461966 | 0.85 | TBXA2R (0.54) | ALDH1A1KMT2AMEN1LMNAAKR1C3 | |
| SCHEMBL10461595 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1LMNATP53 | |
| SCHEMBL11109071 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1LMNATP53 | |
| SCHEMBL10463635 | 0.83 | AKR1C3 (0.53) | ALDH1A1KMT2AMEN1LMNAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |