Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18459329 | 0.84 | CA2 (0.61) | PTGS1PTGS2GAAALDH1A1TDP1 | |
| SCHEMBL10366243 | 0.81 | ALDH1A1 (0.50) | PTGS1PTGS2GAAALDH1A1TDP1 | |
| SCHEMBL26373519 | 0.79 | ALDH1A1 (0.53) | PTGS1PTGS2GAAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10461960 | 0.78 | GAA (0.44) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL8971657 | 0.78 | ALDH1A1 (0.44) | PTGS1PTGS2GAAALDH1A1TDP1 | |
| SCHEMBL8971750 | 0.78 | GAA (0.51) | PTGS1PTGS2GAAALDH1A1TDP1 | |
| SCHEMBL11420770 | 0.76 | CA2 (0.68) | PTGS1PTGS2ALDH1A1CA2CA1 | |
| SCHEMBL8971001 | 0.74 | GSR (0.41) | GAAALDH1A1TDP1CA2CA1 | |
| SCHEMBL8971764 | 0.74 | NR1H4 (0.49) | GAAALDH1A1TDP1CA2POLB | |
| SCHEMBL2320419 | 0.74 | CA2 (0.64) | PTGS1PTGS2GAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263229-A1 | Phenol derivatives, their preparation and the use thereof | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-04-13 | — | — | EP | claimed |
| JP-62029557-A | — | — | None | — | — | JP | disclosed |
| US-4906662-A | Phenol derivatives, their preparation and the use thereof | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0263229-A1 | Phenol derivatives, their preparation and the use thereof | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-04-13 | — | — | EP | disclosed |
| JP-S6229557-A | DILOWER ALKYLPHENOL DERIVATIVE | OTSUKA PHARMACEUT FACTORY INC | 1987-02-07 | — | — | JP | disclosed |