Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463989 | 0.99 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDPOLBADORA1 | |
| SCHEMBL10462405 | 0.89 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDPOLBADORA1 | |
| SCHEMBL10463381 | 0.88 | CNR2 (0.45) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL10464021 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDPOLBADORA1 | |
| SCHEMBL10463271 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDPOLBADORA1 | |
| SCHEMBL10596766 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDPOLBADORA1 | |
| SCHEMBL10463550 | 0.83 | CNR2 (0.42) | ALDH1A1KDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL10462655 | 0.81 | HPGD (0.50) | ALDH1A1KDM4EHPGDPOLBADORA2B | |
| SCHEMBL10460643 | 0.80 | HPGD (0.51) | ALDH1A1KDM4EHPGDPOLBADORA2B | |
| SCHEMBL10464019 | 0.80 | CNR2 (0.41) | ALDH1A1KDM4EHPGDESR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |