Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462363 | 0.98 | BRD4 (0.46) | BRD4CREBBPKMT2AMEN1GFER | |
| SCHEMBL10462364 | 0.86 | BRD4 (0.44) | BRD4CREBBPKMT2AMEN1ALDH1A1 | |
| SCHEMBL10462413 | 0.86 | RAB9A (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL10462641 | 0.86 | ABCB1 (0.43) | BRD4KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10462900 | 0.86 | KMT2A (0.39) | BRD4CREBBPKMT2AMEN1GFER | |
| SCHEMBL10462410 | 0.85 | KMT2A (0.38) | BRD4CREBBPKMT2AMEN1GFER | |
| SCHEMBL10462777 | 0.85 | RAB9A (0.45) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL10463739 | 0.84 | EGFR (0.49) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL10463609 | 0.83 | GFER (0.52) | BRD4KMT2AMEN1GFERALDH1A1 | |
| SCHEMBL10463835 | 0.83 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |