Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461740 | 0.89 | ALPG (0.55) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10461812 | 0.81 | CRBN (0.54) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10463554 | 0.79 | TBXAS1 (0.57) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10461627 | 0.79 | TBXAS1 (0.53) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10461629 | 0.79 | TBXAS1 (0.53) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10462993 | 0.78 | TBXAS1 (0.52) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10462991 | 0.78 | TBXAS1 (0.52) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10461476 | 0.77 | TBXAS1 (0.55) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10838818 | 0.77 | HTR1A (0.56) | HTR1AHTR2AHTR7DRD3DRD4 | |
| Acetic Acid SCHEMBL10463268 | 0.77 | TBXAS1 (0.52) | HTR1AHTR2AHTR7DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921862-A | Carbostyril derivatives as combined thromboxane synthetase and cyclic-amp phosphodiesterase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4792561-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |