SCHEMBL1046405

SCHEMBL1046405

Nc1ccc(Oc2ccc(C(C(F)(F)F)C(F)(F)F)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
TDP1 Q9NUW8 4/20 0.56
CYP3A4 P08684 2/20 0.56
TSHR P16473 1/20 0.56
MAOA P21397 2/20 0.48
MAPT P10636 5/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MAPK1 P28482 3/20 0.47
HPGD P15428 1/20 0.47
MAOB P27338 2/20 0.47
TEAD4 Q15561 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
POLB P06746 1/20 0.45
MITF O75030 1/20 0.45
GAA P10253 1/20 0.45
GFER P55789 1/20 0.45
NLRP1 Q9C000 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30288525 0.88 ALDH1A1 (0.47) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL3645937 0.87 MEN1 (0.42) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL24800705 0.84 ALDH1A1 (0.56) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL7613780 0.83 MAOB (0.58) ALDH1A1CYP3A4TSHRMAOAMAPT
SCHEMBL3754589 0.83 ALDH1A1 (0.59) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL17723029 0.80 TEAD4 (0.47) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL31317722 0.79 TSHR (0.42) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL29950378 0.79 PDE7A (0.46) ALDH1A1CYP3A4TSHRMAOAMAPT
SCHEMBL21628654 0.77 PARP10 (0.63) ALDH1A1TSHRMAPTMAOBKMT2A
SCHEMBL311586 0.76 ALDH1A1 (0.70) ALDH1A1TDP1CYP3A4TSHRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929479-A Carbon-silicon composite material for new energy automobile brake disc and preparation method thereof 安徽绿能技术研究院有限公司 2022-01-14 CN claimed
CN-119081111-A Resin composition 旭化成株式会社 2024-12-06 CN disclosed
CN-118852618-A Resin composition 旭化成株式会社 2024-10-29 CN disclosed
CN-118676106-A Semiconductor device and method for manufacturing the same 旭化成株式会社 2024-09-20 CN disclosed
CN-118363270-A Negative photosensitive resin composition, method for producing cured relief pattern, and semiconductor device 旭化成株式会社 2024-07-19 CN disclosed
US-20240230568-A1 EMBEDDED SENSOR SYSTEM FOR MEASUREMENT AND MONITORING OF THE PORE SOLUTION ELECTRICAL RESISTIVITY IN CONCRETE MATERIALS AND STRUCTURES PENN STATE RES FOUND (US) 2024-07-11 US disclosed
CN-117420732-B Negative photosensitive resin composition and application thereof 明士(北京)新材料开发有限公司 2024-04-16 CN disclosed
CN-113549217-B Polyimide precursor, resin composition containing same, polyimide resin film, and method for producing same 旭化成株式会社 2024-03-08 CN disclosed
CN-117420732-A Negative photosensitive resin composition and application thereof 明士(北京)新材料开发有限公司 2024-01-19 CN disclosed
CN-117120516-A Polyimide, resin composition, polyimide film, and method for producing same 旭化成株式会社 2023-11-24 CN disclosed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 US disclosed
EP-0837870-A1 SYNTHETIC MODIFICATION TO SPINOSYN COMPOUNDS DOWELANCO (US) 1998-04-29 EP disclosed
US-5719256-A CONDENSING CARBOXYL GROUP CONTAINING COMPOUND AND ACTIVE HYDROGEN CONTAINING COMPOUND IN PRESENCE OF HALOIMINIUM SALT AS POLYMERIZATION CATALYST MITSU TOATSU CHEMICALS, INC. (JP) 1998-02-17 US disclosed
US-5710334-A PENDANT ETHER GROUPS, POLYIMIDES WITH IMPROVED SOLUBILITY, MELT FLOW STABILITY, PROCESSABILITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-01-20 US disclosed
US-5708128-A HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INC. (JP) 1998-01-13 US disclosed
WO-1997000265-A1 SYNTHETIC MODIFICATION TO SPINOSYN COMPOUNDS DOWELANCO (US) 1997-01-03 WO disclosed
US-5514748-A POLYMER FOR SLIDING CONTAINING PHENOLIC RESINS AND LUBRICANTS WITH POLYIMIDES MITSUI TOATSU CHEMICALS, INC. (JP) 1996-05-07 US disclosed
US-5512628-A COMBINING A PIPERAZINYLETHYLAMINOCARBONYL-CONTAINING BUTADIENE-ACRYLONITRILE COPOLYMER WITH A MALEIMIDE CONTAINING COMPOUND IN AN ORGANIC SOLVENT; CURABLE TOMOEGAWA PAPER CO., LTD. (JP) 1996-04-30 US disclosed
US-5510189-A COMPRISING A PIPERAZINYLETHYLAMINOCARBONYL-CONTAINING BUTADIENE-ACRYLONITRILE COPOLYMER AND A MALEIMIDE COMPOUND; ADHERED AND CURED AT LOW TEMPERATURE; HEAT RESISTANCE TOMOEGAWA PAPER CO., LTD. (JP) 1996-04-23 US disclosed
US-5196506-A Heat resistance MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-23 US disclosed