SCHEMBL24800705

SCHEMBL24800705

Nc1ccc(Oc2ccc(C(c3ccc(Oc4ccc(N)cc4)cc3)C(F)(F)F)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
TDP1 Q9NUW8 3/20 0.56
CYP3A4 P08684 1/20 0.56
TSHR P16473 1/20 0.56
MAOA P21397 2/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
MAPT P10636 5/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MAPK1 P28482 3/20 0.47
HPGD P15428 1/20 0.47
TEAD4 Q15561 1/20 0.47
MAOB P27338 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
POLB P06746 1/20 0.45
MITF O75030 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7176980 0.87 ESR1 (0.61) ALDH1A1TDP1CYP3A4TSHRESR1
SCHEMBL1046405 0.84 ALDH1A1 (0.56) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL15721669 0.80 ESR1 (0.48) ALDH1A1TDP1TSHRESR1ESR2
SCHEMBL6925377 0.79 ESR1 (0.52) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL9296352 0.78 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4ESR1ESR2
SCHEMBL30288525 0.77 ALDH1A1 (0.47) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL311586 0.76 ALDH1A1 (0.70) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL3146062 0.76 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL10576066 0.75 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL65211 0.75 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022270546-A1 NEGATIVE-TYPE PHOTOSENSITIVE POLYMER, POLYMER SOLUTION, NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, AND SEMICONDUCTOR DEVICE 住友ベークライト株式会社 2022-12-29 WO disclosed
WO-2022270527-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE PHOTOSENSITIVE POLMER, CURED FILM AND SEMICONDUCTOR DEVICE 住友ベークライト株式会社 2022-12-29 WO disclosed
WO-2022270529-A1 NEGATIVE PHOTOSENSITIVE POLYMER, POLYMER SOLUTION, NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, AND SEMICONDUCTOR DEVICE 住友ベークライト株式会社 2022-12-29 WO disclosed
WO-2022270541-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE PHOTOSENSITIVE POLYMER, CURED FILM, AND SEMICONDUCTOR DEVICE 住友ベークライト株式会社 2022-12-29 WO disclosed