Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464172 | 0.84 | HRH3 (0.33) | HRH3OPRD1 | |
| SCHEMBL9372062 | 0.82 | OPRD1 (0.33) | HRH3OPRD1OPRM1OPRK1 | |
| SCHEMBL10254196 | 0.81 | HRH3 (0.35) | HRH3OPRD1OPRK1 | |
| SCHEMBL10464171 | 0.78 | — | — | |
| SCHEMBL20227878 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL6692977 | 0.75 | OPRD1 (0.41) | HRH3OPRD1OPRK1 | |
| SCHEMBL327601 | 0.75 | OPRD1 (0.41) | HRH3OPRD1OPRK1 | |
| SCHEMBL3970107 | 0.75 | OPRD1 (0.41) | HRH3OPRD1OPRK1 | |
| SCHEMBL290880 | 0.75 | — | — | |
| SCHEMBL9372192 | 0.74 | HRH3 (0.35) | HRH3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937242-A | CALCIUM ANTAGONISTS | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-06-26 | — | — | US | disclosed |