Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463840 | 0.92 | HIF1A (0.44) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL10519864 | 0.85 | HSD17B10 (0.50) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL10464424 | 0.85 | HMGB1 (0.43) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL10464426 | 0.84 | CYP3A4 (0.50) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL1374911 | 0.82 | PTPN1 (0.47) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL9252807 | 0.81 | PTPN1 (0.59) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL1129773 | 0.80 | HMGB1 (0.53) | HMGB1CXCL12PTPN1HSD17B10CYP2C9 | |
| SCHEMBL10464425 | 0.76 | ALDH1A1 (0.35) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL10463907 | 0.76 | CYP3A4 (0.48) | PTPN1PTPN2PTPN6HSD17B10CYP2C9 | |
| SCHEMBL10948417 | 0.75 | CYP3A4 (0.47) | HSD17B10CYP2C9HIF1ACYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920091-A | CONTAINING SALICYLIC ACID DERIVATIVE AS ELECTRON ACCEPTING COLOR DEVELOPER; STABLE IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-24 | — | — | US | disclosed |