Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | OGA | O60502 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185606 | 0.99 | ALDH1A1 (0.62) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| SCHEMBL10466693 | 0.88 | OGA (0.56) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| SCHEMBL10464496 | 0.88 | OGA (0.53) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| SCHEMBL5378395 | 0.86 | OGA (0.53) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| SCHEMBL7173774 | 0.86 | OGA (0.55) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| SCHEMBL5723882 | 0.85 | OGA (0.52) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL2584196 | 0.85 | MAPT (0.53) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| SCHEMBL1118526 | 0.85 | OGA (0.54) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| SCHEMBL3436232 | 0.84 | RAB9A (0.55) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| SCHEMBL15888544 | 0.84 | OGA (0.53) | ALDH1A1KMT2AL3MBTL1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | disclosed |
| CN-114450283-A | 3, 6-diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2022-05-06 | — | — | CN | disclosed |
| EP-2925745-B1 | CXCR7 ANTAGONISTS | CHEMOCENTRYX INC (US) | 2018-04-04 | — | — | EP | disclosed |
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |