⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406800 | 1.00 | — | — | |
| SCHEMBL716292 | 0.79 | ALDH1A1 (0.38) | — | |
| SCHEMBL8549913 | 0.77 | CRBN (0.36) | — | |
| SCHEMBL4551233 | 0.76 | — | — | |
| SCHEMBL29662768 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL11096237 | 0.73 | — | — | |
| SCHEMBL1133788 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL7624484 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL11100807 | 0.72 | — | — | |
| SCHEMBL6687753 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918185-A | Process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones and products and starting materials therefor | ELI LILLY AND COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| US-4771135-A | ANTIBIOTIC INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0163452-A1 | A novel process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones | ELI LILLY AND COMPANY (US) | 1985-12-04 | — | — | EP | disclosed |