Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150207 | 0.87 | CA12 (0.48) | CA12CA9CA1CA2CA3 | |
| SCHEMBL10845026 | 0.74 | CA12 (0.50) | CA12CA9CA1CA2CA3 | |
| SCHEMBL29089325 | 0.70 | POLB (0.47) | POLBAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL13071170 | 0.69 | POLB (0.51) | CA12CA9CA2CA3CA4 | |
| SCHEMBL8408030 | 0.69 | NPC1 (0.58) | CA12CA9CA1CA3CA4 | |
| SCHEMBL295803 | 0.69 | CA12 (0.77) | CA12CA9CA1CA2CA3 | |
| SCHEMBL5464496 | 0.69 | GPR55 (0.61) | CA12CA9CA1CA2CA3 | |
| SCHEMBL2274941 | 0.68 | POLB (0.57) | CA12CA9CA1POLBAKR1B1 | |
| SCHEMBL30002655 | 0.68 | POLB (0.57) | CA12CA9CA1POLBAKR1B1 | |
| SCHEMBL11128154 | 0.67 | NPC1 (0.55) | CA12CA9CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956480-A | 7-amino-4-methyl-coumarin-3-carboxyalkyl derivates and fluorescent conjugates thereof | BIOCARB AB (SE) | 1990-09-11 | — | — | US | disclosed |
| EP-0277139-A1 | 7-AMINO-4-METHYL-COUMARIN-3-CARBOXYALKYL DERIVATIVES AND FLUORESCENT CONJUGATES THEREOF. | BIOCARB AB (SE) | 1988-08-10 | — | — | EP | disclosed |
| WO-1987003589-A1 | 7-AMINO-4-METHYL-COUMARIN-3-CABOXYALKYL DERIVATES AND FLUORESCENT CONJUGATES THEREOF | BIOCARB AB (SE) | 1987-06-18 | — | — | WO | disclosed |