Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464925 | 0.87 | CA12 (0.47) | CA12CA1CA2CA4CA5A | |
| SCHEMBL10845026 | 0.87 | CA12 (0.50) | CA12CA1CA2CA4CA5A | |
| SCHEMBL2274941 | 0.81 | POLB (0.57) | CA12CA1CA9POLBAKR1B1 | |
| SCHEMBL30002655 | 0.81 | POLB (0.57) | CA12CA1CA9POLBAKR1B1 | |
| SCHEMBL29089325 | 0.80 | POLB (0.47) | POLBGPR55AKR1B10AKR1B1NPC1 | |
| SCHEMBL11128154 | 0.79 | NPC1 (0.55) | CA12CA1CA2CA4CA5A | |
| SCHEMBL2403666 | 0.77 | RAB9A (0.59) | CA12CA1CA4CA5ACA7 | |
| SCHEMBL21121524 | 0.76 | GPR55 (0.66) | CA12CA2CA4CA7CA3 | |
| SCHEMBL636716 | 0.76 | SLC16A3 (0.64) | NPC1RAB9AKMT2AMEN1SLC16A3 | |
| SCHEMBL6490439 | 0.74 | AKR1B1 (0.54) | CA12CA9AKR1B1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090162839-A1 | DIAGNOSIS AND PROGNOSIS OF CANCER BASED ON TELOMERE LENGTH AS MEASURED ON CYTOLOGICAL SPECIMENS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-06-25 | — | — | US | disclosed |