Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.69 |
| ▸ | GBA1 | P04062 | 7/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.60 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CDK9 | P50750 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1142765 | 0.81 | RAB9A (1.00) | RAB9AGBA1NPC1KMT2AMEN1 | |
| SCHEMBL16899014 | 0.80 | KMT2A (0.77) | RAB9AGBA1NPC1KMT2AMEN1 | |
| SCHEMBL13715658 | 0.78 | RAB9A (0.66) | RAB9AGBA1NPC1KMT2AMEN1 | |
| Diphenylurea SCHEMBL133103 | 0.77 | SMN1; SMN2 (1.00) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL445230 | 0.75 | GBA1 (0.47) | RAB9AGBA1NPC1KMT2AMEN1 | |
| SCHEMBL9317689 | 0.75 | RAB9A (1.00) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31078859 | 0.75 | KMT2A (1.00) | RAB9AGBA1NPC1KMT2AMEN1 | |
| Diphenylurea SCHEMBL3037927 | 0.74 | SMN1; SMN2 (0.94) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| Diphenylurea SCHEMBL30786615 | 0.74 | SMN1; SMN2 (0.94) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| Diphenylurea SCHEMBL28431956 | 0.74 | SMN1; SMN2 (0.94) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933352-A | Bi-functional carbamates of 2-ureado-pyridine compounds | THEODOROPULOS SPYROS (US) | 1990-06-12 | — | — | US | disclosed |