Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.48 |
| ▸ | SCN1A | P35498 | 3/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | THPO | P40225 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11176535 | 0.86 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1TP53SMN1; SMN2GAA | |
| SCHEMBL10466305 | 0.85 | BCHE (0.56) | L3MBTL1ALDH1A1HSD17B10TP53MAPK1 | |
| SCHEMBL2084790 | 0.79 | ALDH1A1 (0.59) | L3MBTL1CYP3A4ALDH1A1HSD17B10KDM4E | |
| SCHEMBL10464989 | 0.79 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL10466678 | 0.76 | TSHR (0.53) | L3MBTL1CYP1A2CYP2C19SMN1; SMN2GAA | |
| SCHEMBL5711769 | 0.76 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1HSD17B10KDM4ETP53 | |
| SCHEMBL10467095 | 0.75 | L3MBTL1 (0.53) | L3MBTL1CYP3A4ALDH1A1HSD17B10KDM4E | |
| SCHEMBL10466047 | 0.73 | L3MBTL1 (0.67) | L3MBTL1CYP3A4ALDH1A1HSD17B10KDM4E | |
| SCHEMBL8229545 | 0.73 | L3MBTL1 (0.67) | L3MBTL1CYP3A4ALDH1A1HSD17B10KDM4E | |
| SCHEMBL5330672 | 0.73 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | claimed |
| US-4943570-A | GASTROINTESTINAL DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-07-24 | — | — | US | disclosed |
| US-4933338-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS, TREATMENT OF GASTROINTESTINAL DISORDERS; CHEMICAL INTERMEDIATES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-06-12 | — | — | US | disclosed |