Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | CLK3 | P49761 | 2/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.34 |
| ▸ | MAP3K19 | Q56UN5 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.34 |
| ▸ | CSNK1G3 | Q9Y6M4 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332375 | 0.77 | HSD17B10 (0.34) | ALDH1A1HSD17B10MAPTDYRK1APIM1 | |
| SCHEMBL25323280 | 0.69 | SNCA (0.34) | ALDH1A1HSD17B10MAPTDYRK1APIM1 | |
| SCHEMBL7331495 | 0.67 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MAPTDYRK1APIM1 | |
| SCHEMBL7331819 | 0.66 | HSD17B10 (0.36) | ALDH1A1HSD17B10MAPTDYRK1APIM1 | |
| SCHEMBL31731877 | 0.63 | ALDH1A1 (0.35) | ALDH1A1HSD17B10MAPTHTTNPSR1 | |
| SCHEMBL11517594 | 0.58 | NOTUM (0.44) | HSD17B10LMNAHTR2C | |
| SCHEMBL8034729 | 0.58 | MAPT (0.55) | ALDH1A1HSD17B10MAPTDYRK1APIM1 | |
| SCHEMBL11515180 | 0.58 | ACHE (0.41) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL8590161 | 0.57 | HSD17B10 (0.44) | ALDH1A1HSD17B10MAPTDYRK1APIM1 | |
| SCHEMBL29114120 | 0.57 | NOX1 (0.42) | ALDH1A1MAPTHTTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968708-A | Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same | NIKKEN CHEMICALS CO., LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0347880-A2 | Imidazo[2,1-b]benzothiazole compounds and antiulcer compositions containing the same | NIKKEN CHEMICALS CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |