Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | HMGCR | P04035 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963246 | 0.98 | RECQL (0.73) | PTPN7RECQLTDP1MEN1KMT2A | |
| SCHEMBL10803234 | 0.98 | RECQL (0.73) | PTPN7RECQLTDP1MEN1KMT2A | |
| SCHEMBL10919003 | 0.98 | RECQL (0.73) | PTPN7RECQLTDP1MEN1KMT2A | |
| SCHEMBL22540052 | 0.88 | PTPN7 (0.70) | PTPN7RECQLTDP1MEN1KMT2A | |
| SCHEMBL5974171 | 0.88 | PTPN7 (0.70) | PTPN7RECQLTDP1MEN1KMT2A | |
| SCHEMBL4453291 | 0.84 | PTPN7 (0.72) | PTPN7RECQLTDP1MEN1KMT2A | |
| SCHEMBL10456798 | 0.84 | PTPN7 (1.00) | PTPN7RECQLTDP1MEN1KMT2A | |
| SCHEMBL31189059 | 0.84 | PTPN7 (1.00) | PTPN7RECQLTDP1MEN1KMT2A | |
| SCHEMBL10458468 | 0.84 | PTPN7 (1.00) | PTPN7RECQLTDP1MEN1KMT2A | |
| SCHEMBL3796753 | 0.84 | PTPN7 (0.72) | PTPN7RECQLTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497827-A | TETRAZOLE, ACYLHYDROXYLAMINE, HYDROXYMETHYLKETONE AND AMIDE DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1985-02-05 | — | — | US | claimed |
| US-4916136-A | LIPOXYGENASE AND CYCLOOXYGENASE INHIBITORS | Centre International de Recherches Dermatologioues C.I.R.D. (FR) | 1990-04-10 | — | — | US | disclosed |
| EP-0104468-B1 | ARACHIDONIC ACID ANALOGUES AS ANTI-INFLAMMATORY AND ANTIALLERGIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-07-23 | — | — | EP | disclosed |
| US-4497827-A | TETRAZOLE, ACYLHYDROXYLAMINE, HYDROXYMETHYLKETONE AND AMIDE DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1985-02-05 | — | — | US | disclosed |