Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465612 | 0.82 | CYP19A1 (0.40) | NTRK1PTPN1TRPV1LMNAHTT | |
| SCHEMBL10464161 | 0.82 | CXCR4 (0.39) | NTRK1KDM4EALDH1A1ABL1TSHR | |
| SCHEMBL10518546 | 0.79 | SLC6A2 (0.46) | NTRK1LMNAMAPTTSHR | |
| SCHEMBL10465337 | 0.77 | EPHX2 (0.49) | EPHX2NR1H4PTPRZ1KDM4EALDH1A1 | |
| SCHEMBL10465910 | 0.74 | PTPRZ1 (0.39) | EPHX2NR1H4NTRK1PTPRZ1KDM4E | |
| SCHEMBL9203686 | 0.72 | CYP3A4 (0.41) | EPHX2NR1H4PTPRZ1ALDH1A1PTPN1 | |
| SCHEMBL10465335 | 0.71 | EPHX2 (0.44) | EPHX2NR1H4PTPRZ1KDM4EALDH1A1 | |
| SCHEMBL13020828 | 0.69 | PTPRZ1 (0.57) | EPHX2NR1H4PTPRZ1KDM4EALDH1A1 | |
| SCHEMBL9790519 | 0.68 | HCAR2 (0.45) | KDM4ETDP1LMNA | |
| SCHEMBL10585982 | 0.68 | SMN1; SMN2 (0.40) | ALDH1A1MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939155-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| US-4877446-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | disclosed |
| EP-0277520-A2 | Parasiticide on a pyrimidine derivative basis | BAYER AG (DE) | 1988-08-10 | — | — | EP | disclosed |