Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465337 | 0.80 | EPHX2 (0.49) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL10518362 | 0.77 | SLC6A4 (0.46) | ALDH1A1TDP1MAPTPPARG | |
| SCHEMBL13020828 | 0.72 | PTPRZ1 (0.57) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL10465331 | 0.71 | EPHX2 (0.44) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL13169964 | 0.68 | PTPRZ1 (0.61) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| Ethane SCHEMBL11401460 | 0.67 | PTPRZ1 (0.59) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL963353 | 0.66 | PTPRZ1 (0.63) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL10655803 | 0.66 | ALDH1A1 (0.52) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL10655795 | 0.66 | PTPRZ1 (0.58) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL10582270 | 0.66 | RIPK1 (0.43) | ALDH1A1KDM4ETDP1RAB9ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939155-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| US-4877446-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | disclosed |
| EP-0277520-A2 | Parasiticide on a pyrimidine derivative basis | BAYER AG (DE) | 1988-08-10 | — | — | EP | disclosed |