Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465335 | 0.80 | EPHX2 (0.44) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL13020828 | 0.78 | PTPRZ1 (0.57) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL13169964 | 0.77 | PTPRZ1 (0.61) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL9198566 | 0.77 | MAOB (0.46) | PTPN1LMNAHTT | |
| SCHEMBL10465331 | 0.77 | EPHX2 (0.44) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL9626513 | 0.77 | RIPK1 (0.47) | KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL10655803 | 0.75 | ALDH1A1 (0.52) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL8951998 | 0.74 | HPGD (0.44) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11081323 | 0.73 | PTPRZ1 (0.69) | EPHX2NR1H4PTPRZ1PTPN1ALDH1A1 | |
| SCHEMBL10741181 | 0.73 | EPHX2 (0.49) | EPHX2NR1H4ALDH1A1TRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198429-B2 | Heterocyclic alkanol-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2782904-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLCTUAL PROPERTY GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| WO-2013076227-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |
| US-4939155-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| US-4877446-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | ERG28, CBR3, MYB | EPHX2 1398/4885NR1H4 4664/4885PTPRZ1 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.