SCHEMBL10465601

SCHEMBL10465601

CCCO[Si](CCCCCCC1CO1)(OCCC)OCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
TDP1 Q9NUW8 1/20 0.40
EPHX1 P07099 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
SPHK2 Q9NRA0 2/20 0.34
SPHK1 Q9NYA1 2/20 0.32
ENPP2 Q13822 1/20 0.31
LPAR2 Q9HBW0 1/20 0.31
TSHR P16473 1/20 0.31
CYP1A2 P05177 2/20 0.30
PRKD3 O94806 1/20 0.30
PRKCG P05129 1/20 0.30
PRKCB P05771 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCH P24723 1/20 0.30
PRKCI P41743 1/20 0.30
PRKCE Q02156 1/20 0.30
PRKCQ Q04759 1/20 0.30
PRKCZ Q05513 1/20 0.30
PRKCD Q05655 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10463923 1.00 ALDH1A1 (0.55) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK2
SCHEMBL3799053 0.98 ALDH1A1 (0.52) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK2
SCHEMBL28264255 0.92 ALDH1A1 (0.50) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK2
SCHEMBL29175247 0.90 ALDH1A1 (0.47) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK2
SCHEMBL10465672 0.90 ALDH1A1 (0.55) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK2
SCHEMBL871430 0.86 ALDH1A1 (0.53) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL3066970 0.86 ALDH1A1 (0.53) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK1
SCHEMBL29124751 0.84 ALDH1A1 (0.52) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK2
SCHEMBL29089025 0.84 ALDH1A1 (0.53) ALDH1A1TDP1EPHX1SMN1; SMN2SPHK2
SCHEMBL267044 0.84 ALDH1A1 (0.50) ALDH1A1TDP1EPHX1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4966922-A POLYSILOXANE MODIFIED WITH BOTH HYDROLYZABLE LEAVING GROUPS AND EPOXY GROUPS CATALYZED WITH A CONDENSATION CURE CATALYST AND ONIUM PHOTOINITIATOR GENERAL ELECTRIC COMPANY (US) 1990-10-30 US disclosed
EP-0345575-A1 Dual curable silicone compositions GENERAL ELECTRIC COMPANY (US) 1989-12-13 EP disclosed
EP-0016265-B1 POWDER COMPOSITION, PROCESS FOR THE PREPARATION THEREOF, AND USE THEREOF IN COATING A GLASS CONTAINER CELANESE CORPORATION (US) 1983-09-14 EP disclosed
US-4260066-A Method of powder coating a glass container and product produced CELANESE CORPORATION (US) 1981-04-07 US disclosed
US-4256232-A Powder composition and method of preparation CELANESE CORPORATION (US) 1981-03-17 US disclosed
EP-0016265-A1 Powder composition, process for the preparation thereof, and use thereof in coating a glass container CELANESE CORPORATION (US) 1980-10-01 EP disclosed
US-4207359-A Method of powder coating a glass container CELANESE CORPORATION (US) 1980-06-10 US disclosed
US-4201834-A Powder composition and method of preparation CELANESE CORPORATION (US) 1980-05-06 US disclosed
US-4171056-A Coated bottle and method of coating CELANESE CORPORATION (US) 1979-10-16 US disclosed
US-4163031-A Powder composition and method of preparation CELANESE CORPORATION (US) 1979-07-31 US disclosed