Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCH | P24723 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3799053 | 0.91 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TDP1EPHX1SPHK2 | |
| SCHEMBL29089025 | 0.91 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TDP1EPHX1SPHK1 | |
| SCHEMBL10463923 | 0.90 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TDP1EPHX1SPHK1 | |
| SCHEMBL10465601 | 0.90 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2TDP1EPHX1SPHK1 | |
| SCHEMBL28954820 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TDP1EPHX1SPHK1 | |
| SCHEMBL29011016 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2TDP1EPHX1SPHK1 | |
| SCHEMBL267044 | 0.84 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TDP1EPHX1 | |
| SCHEMBL29175247 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TDP1EPHX1SPHK1 | |
| SCHEMBL7186759 | 0.83 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL7786205 | 0.82 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TDP1EPHX1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966922-A | POLYSILOXANE MODIFIED WITH BOTH HYDROLYZABLE LEAVING GROUPS AND EPOXY GROUPS CATALYZED WITH A CONDENSATION CURE CATALYST AND ONIUM PHOTOINITIATOR | GENERAL ELECTRIC COMPANY (US) | 1990-10-30 | — | — | US | disclosed |
| EP-0345575-A1 | Dual curable silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1989-12-13 | — | — | EP | disclosed |
| US-4208503-A | PROTECTIVE COATINGS, SIZING AGENTS | SWS SILICONES CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |