Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464599 | 0.87 | NPC1 (0.60) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL10464600 | 0.87 | NPC1 (0.60) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL10466168 | 0.86 | NPC1 (0.71) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL10466169 | 0.86 | NPC1 (0.71) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL6841774 | 0.85 | ALDH1A1 (0.59) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL10465508 | 0.85 | NPC1 (0.58) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL10465934 | 0.85 | NPC1 (0.58) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL10236929 | 0.82 | RAB9A (0.82) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL11350421 | 0.82 | RAB9A (0.82) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL19962767 | 0.81 | RAB9A (0.70) | NPC1RAB9AMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397746-A1 | CONDENSATION POLYMERS CONTAINING METHINE ULTRAVIOLET RADIATION-ABSORBING RESIDUES AND SHAPED ARTICLES PRODUCED THEREFROM | EASTMAN KODAK COMPANY (US) | 1990-11-22 | — | — | EP | disclosed |
| EP-0326287-A2 | Condensation polymers containing methine ultraviolet radiation-absorbing residues and shaped articles produced therefrom | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-08-02 | — | — | EP | disclosed |
| WO-1989006663-A1 | CONDENSATION POLYMERS CONTAINING METHINE ULTRAVIOLET RADIATION-ABSORBING RESIDUES AND SHAPED ARTICLES PRODUCED THEREFROM | EASTMAN KODAK COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |
| US-4845187-A | POLYESTERS | EASTMAN KODAK COMPANY (US) | 1989-07-04 | — | — | US | disclosed |