Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494203 | 0.83 | L3MBTL1 (0.72) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10467775 | 0.82 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL330024 | 0.82 | L3MBTL1 (0.70) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL5416733 | 0.81 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL570190 | 0.80 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL31314987 | 0.80 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL15016454 | 0.77 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL13220098 | 0.77 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL31448310 | 0.77 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7591549 | 0.77 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943570-A | GASTROINTESTINAL DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-07-24 | — | — | US | disclosed |
| US-4933338-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS, TREATMENT OF GASTROINTESTINAL DISORDERS; CHEMICAL INTERMEDIATES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-06-12 | — | — | US | disclosed |
| CN-87102916-A | Benzimidazole sulfonamides and imidazopyridine sulfonamides, their preparation and their use as pharmaceuticals | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | disclosed |