Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314987 | 1.00 | L3MBTL1 (0.68) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 | |
| SCHEMBL22494203 | 0.84 | L3MBTL1 (0.72) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 | |
| SCHEMBL330024 | 0.82 | L3MBTL1 (0.70) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 | |
| SCHEMBL13220098 | 0.81 | L3MBTL1 (0.64) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 | |
| SCHEMBL830431 | 0.81 | L3MBTL1 (0.68) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 | |
| SCHEMBL29815201 | 0.81 | L3MBTL1 (0.68) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 | |
| SCHEMBL935551 | 0.81 | L3MBTL1 (1.00) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 | |
| SCHEMBL31255344 | 0.81 | L3MBTL1 (1.00) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 | |
| SCHEMBL10336742 | 0.81 | L3MBTL1 (0.68) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 | |
| SCHEMBL516854 | 0.81 | L3MBTL1 (0.68) | L3MBTL1ALOX12ALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240139194-A1 | PREPARATION AND METHODS OF USE FOR ORTHO-ARYL 5-MEMBERED HETEROARYL-CARBOXAMIDE CONTAINING MULTI-TARGETED KINASE INHIBITORS | VIBLIOME THERAPEUTICS, LLC | 2024-05-02 | — | — | US | disclosed |
| CN-115819353-B | Method for preparing 2-arylamino benzimidazole and N1-aryl-2-amino benzimidazole | 长沙晶易医药科技股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-115819353-A | Method for preparing 2-aryl amino benzimidazole and N1-aryl-2-amino benzimidazole | 长沙晶易医药科技股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
| WO-2022129256-A1 | SELECTIVE HDAC6 INHIBITOR | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2022-06-23 | — | — | WO | disclosed |
| US-11174246-B2 | Direct AMPK activators | RIGEL PHARMACEUTICALS, INC. (US) | 2021-11-16 | — | — | US | disclosed |
| EP-3442961-B1 | AGRICULTURAL CHEMICALS | REDAG CROP PROT LTD (GB) | 2021-03-24 | — | — | EP | disclosed |
| WO-2021032033-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2021-02-25 | — | — | WO | disclosed |
| EP-3187584-B1 | METHOD FOR NON-ENZYMATIC COMBINATION OF NUCLEIC ACID CHAINS | JAPAN SCIENCE & TECH AGENCY (JP) | 2021-02-24 | — | — | EP | disclosed |
| US-20210032229-A1 | PYRIDINE RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2021-02-04 | — | — | US | disclosed |
| US-10570385-B2 | Method for non-enzymatic combination of nucleic acid chains | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2020-02-25 | — | — | US | disclosed |
| WO-2002032422-A2 | EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |
| WO-2001030408-A2 | ADHESIVE COMPOSITION OVER A BIOACTIVE POLYMERIZATION INITIATOR | CLOSURE MEDICAL CORPORATION (US) | 2001-05-03 | — | — | WO | disclosed |
| EP-0426193-B1 | Silver halide photographic material and processing solution and process for the processing thereof | FUJI PHOTO FILM CO LTD (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5272044-A | Silver halide photographic material and processing solution and process for the processing thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-21 | — | — | US | disclosed |
| US-5149700-A | Antiarrhythmic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| US-5097042-A | With sulfo, sulfonato or tertiary amine group, acid salts | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-17 | — | — | US | disclosed |
| WO-1991018904-A1 | SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |
| EP-0426193-A1 | Silver halide photographic material and processing solution and process for the processing thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |
| US-4293703-A | Imidazole or imidazoline substituted ureas | MERCK & CO., INC. (US) | 1981-10-06 | — | — | US | disclosed |
| US-4241072-A | Substituted ureas and processes for their preparation | MERCK & CO., INC. (US) | 1980-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240139194-A1 | PREPARATION AND METHODS OF USE FOR ORTHO-ARYL 5-MEMBERED HETEROARYL-CARBOXAMIDE CONTAINING MULTI-TARGETED KINASE INHIBITORS | ABL1, ERBB2, MAP3K2 | L3MBTL1 4194/4885ALOX12 4672/4885ALDH1A1 3761/4885 |
| US-10570385-B2 | Method for non-enzymatic combination of nucleic acid chains | RNGTT, NSUN2, POLRMT | L3MBTL1 645/4885ALOX12 2562/4885ALDH1A1 1807/4885 |
| US-20210032229-A1 | PYRIDINE RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | CBR3, CBR1, H1-0 | L3MBTL1 2335/4885ALOX12 2671/4885ALDH1A1 1438/4885 |
| US-11174246-B2 | Direct AMPK activators | PRKAA1, PRKAG1, PRKAB1 | L3MBTL1 2257/4885ALOX12 3667/4885ALDH1A1 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.