Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24630965 | 1.00 | ADRB2 (0.49) | ADRB2TSHRHIF1AADRB1CYP1A2 | |
| SCHEMBL11474610 | 0.82 | ADRB2 (0.52) | ADRB2TSHRHIF1AADRB1CYP1A2 | |
| SCHEMBL11476231 | 0.82 | ADRB2 (0.52) | ADRB2TSHRHIF1AADRB1CYP1A2 | |
| SCHEMBL11603315 | 0.82 | ADRB2 (0.52) | ADRB2TSHRHIF1AADRB1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11487096 | 0.81 | ADRB2 (0.54) | ADRB2TSHRHIF1AADRB1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11487093 | 0.81 | ADRB2 (0.54) | ADRB2TSHRHIF1AADRB1CYP1A2 | |
| SCHEMBL22864240 | 0.80 | ADRB2 (0.48) | ADRB2TSHRHIF1AADRB1CYP1A2 | |
| SCHEMBL11490380 | 0.78 | BLM (0.47) | ADRB2TSHRHIF1AADRB1NFKB1 | |
| SCHEMBL30988826 | 0.78 | CYP3A4 (0.38) | TSHRTDP1CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL29256510 | 0.78 | CYP3A4 (0.38) | TSHRTDP1CYP3A4KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960783-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | claimed |