Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888122 | 0.78 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL8887806 | 0.78 | TSHR (0.36) | MAPTMEN1KMT2ATSHRNPC1 | |
| SCHEMBL7203141 | 0.75 | MEN1 (0.31) | MEN1KMT2A | |
| Water SCHEMBL9326435 | 0.70 | — | — | |
| SCHEMBL8889147 | 0.66 | ELANE (0.46) | ALDH1A1MEN1KMT2AIDH1NPC1 | |
| SCHEMBL3736173 | 0.59 | MEN1 (0.55) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL18262658 | 0.58 | FPR2 (0.47) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL18262657 | 0.58 | FPR2 (0.47) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8806938 | 0.57 | CA9 (0.43) | MAPTALDH1A1 | |
| SCHEMBL10809442 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923856-A | Penem compounds | BEECHAM GROUP P.L.C. (GB) | 1990-05-08 | — | — | US | disclosed |
| EP-0321186-A1 | 6-(Substituted methylene)penems | BEECHAM GROUP PLC (GB) | 1989-06-21 | — | — | EP | disclosed |