Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907437 | 0.81 | ELANE (0.41) | ELANEL3MBTL1ALDH1A1GAAKMT2A | |
| SCHEMBL679071 | 0.81 | ELANE (0.41) | ELANEL3MBTL1ALDH1A1GAAKMT2A | |
| SCHEMBL9538102 | 0.77 | ELANE (0.37) | ELANEKMT2AKDM4EHSD17B10MEN1 | |
| SCHEMBL9478030 | 0.71 | TDP1 (0.61) | L3MBTL1IDH1ALDH1A1KMT2AKDM4E | |
| SCHEMBL9478037 | 0.71 | TDP1 (0.61) | L3MBTL1IDH1ALDH1A1KMT2AKDM4E | |
| SCHEMBL10419993 | 0.70 | ELANE (0.46) | ELANERXFP1L3MBTL1KMT2ANPC1 | |
| SCHEMBL9782704 | 0.69 | ELANE (0.53) | ELANEPOLBSMN1; SMN2 | |
| SCHEMBL9782546 | 0.69 | ELANE (0.67) | ELANEIDH1KMT2APOLBMEN1 | |
| SCHEMBL8806354 | 0.68 | ELANE (0.40) | ELANEPOLB | |
| SCHEMBL8809929 | 0.68 | ELANE (0.38) | ELANEALDH1A1KMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602250-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM P.L.C. (GB) | 1997-02-11 | — | — | US | disclosed |