Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18593912 | 0.83 | CYP3A4 (0.39) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL4918423 | 0.82 | APEX1 (0.45) | DRD4CA2CA4 | |
| SCHEMBL10255927 | 0.78 | GAA (0.36) | DRD4CA1CA9MAPTKMT2A | |
| SCHEMBL22390790 | 0.78 | CYP3A4 (0.43) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL8126372 | 0.76 | CYP3A4 (0.37) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL22653561 | 0.75 | TDP1 (0.45) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL11232970 | 0.73 | TDP1 (0.43) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL5550394 | 0.72 | TTR (0.58) | TSHRTDP1ALOX15CA2LMNA | |
| SCHEMBL7969500 | 0.72 | HTR1D (0.40) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL378361 | 0.72 | TAAR1 (0.34) | CYP3A4TSHRTDP1DRD4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61085444-A | — | — | None | — | — | JP | disclosed |
| CN-111171329-A | Plastic dilatancy polymer and method for realizing dilatancy thereof | 翁秋梅 | 2020-05-19 | — | — | CN | disclosed |
| EP-2137220-B1 | AROMATIC URETHANE ACRYLATES HAVING A HIGH REFRACTIVE INDEX | COVESTRO DEUTSCHLAND AG (DE) | 2017-10-18 | — | — | EP | disclosed |
| US-8987304-B2 | Antituberculous composition comprising oxazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-24 | — | — | US | disclosed |
| US-7981987-B2 | Aromatic urethane acrylates having a high refractive index | BAYER MATERIALSCIENCE AG (DE) | 2011-07-19 | — | — | US | disclosed |
| EP-2269694-A2 | Antituberculous composition comprising oxazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-01-05 | — | — | EP | disclosed |
| CN-101668782-A | Aromatic urethane acrylates with high refractive index | BAYER MATERIALSCIENCE AG | 2010-03-10 | — | — | CN | disclosed |
| EP-2137220-A1 | AROMATIC URETHANE ACRYLATES HAVING A HIGH REFRACTIVE INDEX | Bayer MaterialScience AG (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20090275528-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-11-05 | — | — | US | disclosed |
| US-20080312403-A1 | AROMATIC URETHANE ACRYLATES HAVING A HIGH REFRACTIVE INDEX | BAYER MATERIALSCIENCE AG (DE) | 2008-12-18 | — | — | US | disclosed |
| WO-2008125199-A1 | AROMATIC URETHANE ACRYLATES HAVING A HIGH REFRACTIVE INDEX | BAYER MATERIALSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| WO-2007043542-A9 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 2008-05-08 | — | — | WO | disclosed |
| JP-S6185444-A | PRODUCTION OF FLAME-RETARDANT PHENOLIC RESIN LAMINATE | HITACHI CHEM CO LTD | 1986-05-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275528-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OXA1L, ARG1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CYP3A4 72/4885TSHR 1022/4885TDP1 4107/4885 |
| US-20080312403-A1 | AROMATIC URETHANE ACRYLATES HAVING A HIGH REFRACTIVE INDEX | ACR, UTS2R, MUS81 | CYP3A4 1722/4885TSHR 3629/4885TDP1 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.