Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116670 | 0.88 | GAA (0.53) | GAAMAPTALDH1A1CDK1NLRP3 | |
| SCHEMBL9661941 | 0.81 | MAPT (0.34) | GAAMAPTALDH1A1NLRP3KDM4E | |
| Pyrazosulfuron Ethyl SCHEMBL2440654 | 0.80 | GAA (0.45) | GAAMAPTALDH1A1CDK1KDM4E | |
| SCHEMBL1535829 | 0.79 | GAA (0.53) | GAAMAPTALDH1A1CDK1NLRP3 | |
| SCHEMBL9661255 | 0.79 | GAA (0.53) | GAAMAPTALDH1A1CDK1NLRP3 | |
| SCHEMBL21246925 | 0.78 | GAA (0.43) | GAAMAPTALDH1A1CDK1NLRP3 | |
| SCHEMBL27317318 | 0.78 | FBP1 (0.41) | GAAMAPTCDK1NLRP3NPC1 | |
| 3,6 Dichloromethoxybenzoic Acid SCHEMBL20723789 | 0.77 | GAA (0.45) | GAAMAPTALDH1A1CDK1KDM4E | |
| SCHEMBL11374847 | 0.76 | GAA (0.44) | GAAMAPTALDH1A1CDK1KDM4E | |
| SCHEMBL9660372 | 0.76 | GAA (0.50) | GAAMAPTALDH1A1CDK1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946496-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-07 | — | — | US | claimed |